QuidelOrtho Science BYTES Podcast

Why Convalescent Plasma for COVID-19

Why Convalescent Plasma for COVID-19?

 

In this episode of Ortho Science BYTES host, Matt Dawson discuss why COVID-19 Convalescent Plasma has been used as a treatment and what are the scientific and clinical basis for its use with Dr. Lily Li.  

 

About our Speaker: 

Dr. Lily Li is the Medical Safety Officer at Ortho Clinical Diagnostics responsible for evaluating potential medical risks and guiding risk mitigation of all marketed products. She also serves as a Medical Director at Medical and Scientific Affairs providing evidence-based support to Ortho’s current and future products. Prior to joining Ortho, Lily had ten years of pharmaceutical R&D experience in Johnson & Johnson and led and advanced multiple programs of biologics and cell therapies through development. Lily obtained her Medical Degree from Peking University, China, and her Ph.D. in Immunology from the University of Alberta, Canada. She completed her post-doctoral training at the Scripps Research Institutes, San Diego. Lily is the author of more than 40 scientific articles and has filed 17 patent applications.

 

References and Links: 

• Treatment of 5 Critically Ill Patients With COVID-19 With Convalescent Plasma; Shen at al. JAMA. 2020;323(16):1582-1589. Published online March 27, 2020.
• The feasibility of convalescent plasma therapy in severe COVID-19 patients: a pilot study, Duan et al, Mar 2020, medRxiv preprint doi: https://doi.org/10.1101/2020.03.16.20036145
• Effect of Convalescent Plasma Therapy on Time to Clinical Improvement in Patients With Severe and Life-threatening COVID-19: A Randomized Clinical Trial, Li et al, JAMA, 2020 Jun 3. doi: 10.1001/jama.2020.10044.
• Convalescent plasma treatment of severe COVID-19: A matched 1 control study, S. T. H. Liu, et al, May 22, 2020, medRxiv preprint doi: https://doi.org/10.1101/2020.05.20.20102236.
• Convalescent Plasma to Treat COVID-19. Possibilities and Challenges; John D. Roback, MD, PhD; Jeannette Guarner, MD. JAMA April 28, 2020 Volume 323, Number 16
• The convalescent sera option for containing COVID-19 Arturo Casadevall, Liise-anne Pirofski. J Clin Invest. 2020;130(4):1545-1548.
   FDA site https://www.fda.gov/

You, a Blood Donor: Be part of 200 years of Transfusion Medicine’s History

You, a Blood Donor: Be part of 200 years of Transfusion Medicine’s History

 

In this short program, entitled "You, a Blood Donor: Be part of 200 years of Transfusion Medicine’s History," our own Tony Casina, Transfusion Medicine Consultant, takes us through key milestones in the History of Transfusion Medicine and brings us to today and how the community met the challenge to maintain a safe and adequate blood supply during the COVID-19 pandemic. 
 

Listen in as he discusses the honorable role of a donor of blood products, which can save up to three lives, and thanks the heroes who make this happen.

 

About our Speaker: 

Tony S. Casina, MT(ASCP)SBB has worked in the blood banking industry for over 40 years with much of it in the commercial blood bank reagent manufacturers sector with hospital experience as a medical technologist and blood bank manager. Tony has provided technical support to laboratories throughout the world utilizing Ortho’s reagents and immunohematology test systems.  He has tested some of the most challenging antibody problems as part of his reference laboratory experience. Tony has been an active participant in the AABB serving on committees and currently on the AABB Board of Directors. He has contributed as a presenter to AABB and regional blood bank meetings educational programs. He was extensively involved in the development of the ORTHO VISION® Analyzer Platform

 

References and Links: 

• Clinical Practice of Transfusion Medicine, 2^nd Ed. 1989 Chapter 2: Petz LD and Swisher SN, Churchill Livingstone   
• https://www.redcrossblood.org/donate-blood/blood-donation-process/what-happens-to-donated-blood/blood-transfusions/history-blood-transfusion.html
• http://www.aabb.org/tm/Pages/highlights.aspx
• https://www.history.com/news/blood-plasma-covid-19-measles-spanish-flu